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Prognostic significance of interferon regulating factor 4 (IRF4) in...

AbstractPurposeThe transcription factor IRF4 regulates immunoglobulin class switch recombination as well as plasma cell differentiation. We examined the prognostic significance of IRF4 expression in...

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Subtype-specific prognostic impact of different immune signatures in...

AbstractBackgroundThe role of different subtypes of immune cells is still a matter of debate.MethodsWe compared the prognostic relevance for metastasis-free survival (MFS) of a B-cell signature (BS), a...

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New aspects in deriving health-based guidance values for bromate in swimming...

AbstractBromate, classified as a EU CLP 1B carcinogen, is a typical by-product of the disinfection of drinking and swimming pool water. The aim of this study was (a) to provide data on the occurrence...

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